基于情境感知工具辅助碎片化学习行为的研究

碎片化学习难以集中记录,存在无法迅速定位到自己需要的学习内容等用户体验问题.传统方法不能采集真实情境下的用户数据,无法满足研究人员的研究需求.基于此,开发一种基于用户行为的捕捉工具——CAUX(Context-Aware User Experience,CAUX),设计了具有情境感知能力的数据采集模块,自动捕捉指定App内的用户行为数据.CAUX对用户干扰性低,可以辅助研究人员捕捉典型的碎片化学习行为.对利用CAUX采集到的数据进行处理,并结合人工方法进行分析,可以发现不同情境下的用户行为和用户体验问题.     

催化剂级配技术在加氢改质装置上的工业应用

基于柴油产品质量升级的需求,中国石化大连石油化工研究院(FRIPP)开发了FHIDW加氢改质技术及配套FF-46加氢精制催化剂、FC-14B加氢改质催化剂和FDW-3临氢降凝催化剂.该技术及催化剂级配体系在格尔木炼油厂0.8 Mt·a-1加氢改质装置上的工业应用情况表明,级配催化剂体系对原料适应性强,装置运转平稳,操作灵活性高,催化剂失活速率慢,产品分布合理且质量优异,在降低柴油产品凝点的同时可以明显改善其密度和十六烷值,解决了改造前装置生产重柴油密度偏低的问题,为炼油厂生产符合国V质量标准的柴油提供了技术保障.     

Nanovaccine-Mediated Cell Selective Delivery of Neoantigens Potentiating Adoptive Dendritic Cell Transfer for Personalized Immunization

Neoantigen vaccines and adoptive dendritic cell (DC) transfer are major clinical approaches to initiate personalized immunity in cancer patients. However, the immunization efficacy is largely limited by the in vivo trajectory including neoantigens’ access to resident DCs and DCs’ access to lymph nodes (LNs). Herein, an innovative strategy is proposed to improve personalized immunization through neoantigen-loaded nanovaccines synergized with adoptive DC transfer. It is found that it enables selective delivery of neoantigens to resident DCs and macrophages by coating cancer cell membranes onto neoantigen-loaded nanoparticles. In addition, the nanovaccines promote the secretion of chemokine C-C motif ligand 2 (CCL2), CCL3, and C-X-C motif ligand 10 from macrophages, thus potentiating the access of transferred DCs to LNs. This immunization strategy enables coordinated delivery of identified neoantigens and autologous tumor lysate-derived undefined antigens, leading to initiation of antitumor T cell immunity in a personalized manner. It significantly inhibits tumor growth in prophylactic and established mouse tumor models. The findings provide a new vision for potentiating adoptive cell transfer by nanovaccines, which may open the door to a transformative possibility for improving personalized immunization.     

基于图像分割技术的图像数字水印算法研究

针对数字图像水印技术,通过对闭运算得到的图像再进行开运算,使实验得到的图像区域较为完整,采用4×4的正方形结构元素,使得图像区域有更多的白色像素被置为黑色,对图像进行取反操作,能够对图像区域的非连通区域进行填充.希望能够利用精确的图像分割算法,实现对复杂版面的文档图像的有效切割,在一定程度上对图像数字水印的推广起到促进作用.     

肇庆市固体废物产业发展方向探索

本文以肇庆市固体废物产业发展为实例,阐明全市固体废物产业发展现状以及发展方向,并提出了相应的策略。     

多机电力系统非线性自适应励磁控制器的设计

为了增强多机电力系统的动态稳定性,提升电力系统平抑负荷扰动的能力,本文提出了一种基于自适应反步技术的非线性自适应励磁控制方案.由于发电机的机械功率和阻尼系数受系统运行状态的影响,因此可以直接视为未知数,利用自适应定律估算出来这些未知量.根据李雅普诺夫(Lyapunov)函数的形式推导出自适应规律,保证发电机的转子角速度、机端电压、输出功率等不同物理量均收敛.然后在4机11母线的电力系统输电线路上仿真三相短路故障,测量转子转速偏差,对所提出的控制方案进行评估,并与现有的反步控制器和常规电力系统稳定器(CPSS)进行了比较.根据仿真结果,本文所提出的方法比现有的两种控制器的控制效果更有效.     

A Highly Sensitive,Reversible, and Bidirectional Humidity Actuator by Calcium Carbonate Ionic Oligomers Incorporated Poly(Vinylidene Fluoride)

Sensitivity and multi-directional motivation are major two factors for developing optimized humidity-response materials, which are promising for sensing, energy production, etc. Organic functional groups are commonly used as the water sensitive units through hydrogen bond interactions with water molecules in actuators. The multi-coordination ability of inorganic ions implies that the inorganic ionic compounds are potentially superior water sensitive units. However, the particle forms of inorganic ionic compounds produced by classical nucleation limit the number of exposed ions to interact with water. Recent progress on the inorganic ionic oligomers has broken through the limitation of classical nucleation, and realized the molecular-scaled incorporation of inorganic ionic compounds into an organic matrix. Here, the incorporation of hydrophilic calcium carbonate ionic oligomers into hydrophobic poly(vinylidene fluoride) (PVDF) is demonstrated. The ultra-small calcium carbonate oligomers within a PVDF film endow it with an ultra-sensitive, reversible, and bidirectional response. The motivation ability is superior to other bidirectional humidity-actuators at present, which realizes self-motivation on an ice surface, converting the chemical potential energy of the humidity gradient from ice to kinetic energy.     

供水管网DMA优化分区设计方案

实施独立计量分区(district metered area,DMA)是辅助供水管网管理和漏损识别的重要手段.图划分算法是进行DMA分区的方法之一,常规图划分算法应用中,存在解空间受限、分区后原水流状态易发生较大改变、形成较多串联分区(对流量计算不利)的缺点.在常规图划分算法基础上进行了改进:粗化阶段按照特定规则匹配、合并非输水干管两端的节点,形成简化的管网拓扑结构;分区阶段得到管网初步分区方案;细化阶段提出基于贪心算法、枚举算法、蒙特卡洛算法的分区调整方法,结合改进的仪表安置方法、水力模拟、优劣解距离法(technique for order preference by similarity to an ideal solution,TOPSIS),对分区方案进行调整.将该方法应用于YX市供水管网,成功进行了分区.